The opioid epidemic has had devastating health, social, and economic consequences for families across the U.S., with a disproportionate impact in rural areas. Non-medical opioid use and opioid use disorder during pregnancy are associated with poor maternal outcomes and adverse effects among infants. The diagnosis of maternal opioid use disorder in the U.S. increased disproportionately in rural counties from 2004 to 2013, indicating the need for rural-tailored information to inform opioid programs and policies.This analysis will describe the rates and predictors of non-medical opioid use prior to and during pregnancy and maternal diagnosis of opioid use disorder at birth, based on rural or urban maternal residence and rural or urban hospital location. It will inform targeting of resources to combat the opioid epidemic in rural communities.
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